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Skin hyperpigmentation in Graves´ disease without Addison: Case report

VOLUMEN 6 - NÚMERO 1 / Enero-Marzo (Clinical Case)


Guillermo Enrique Rico-Rubio, Servicio de Dermatología, Hospital Regional número 1
María de la Paz Montoya-Hidalgo, Servicio de Patología, Hospital Regional número 1
Carla Valentina Valencia-Méndez, Servicio de Endocrinología, Centro Médico Nacional del Noroeste. Ciudad Obregón, Son.; Instituto Mexicano del Seguro Social

Increased cutaneous pigmentation occurs in several systemic diseases: the most well-known of these is Addison´s disease in which hyperpigmentation is generalized and represents an accentuation of normal pigment distribution; it often occurs preferentially on the mucosal surface (oral mucosa, areola, gums, and tongue), sexual areas (nipples, areola, axilla, perineum, and genitalia) or points of pressure (elbows, knees, skin folds, and palmer creases).

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